Adequate Primaquine for Vivax Malaria
نویسندگان
چکیده
منابع مشابه
Adequate primaquine for vivax malaria.
BACKGROUND Treatment of vivax malaria with primaquine prevents the relapse of infection from residual liver stages of the parasite. Inadequate dosage is related to a higher relapse risk. METHODS A comparison was made of vivax malaria relapse-prevention treatments with primaquine 22.5 mg or 30 mg daily for 14 days on 146 reports to the Australian Army Central Malaria Register. RESULTS The lo...
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Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 12, No. 11, November 2006 1795 contacts with clandestine gold panners, mainly Brazilian illegal residents. This population, in which malaria incidence is almost impossible to evaluate, comes from Amapa State, where the incidence of malaria is increasing (5). In 2003, 60.9% of patients with malaria cases at Cayenne Hospital had a Brazilian na...
متن کاملCan primaquine therapy for vivax malaria be improved?
The incidence and range of endemic malaria caused by Plasmodium vivax has expanded during the past 30 years. This parasite forms hypnozoites in the liver, creating a persistent reservoir of infection. Primaquine (PQ), introduced 50 years ago, is the only drug available to eliminate hypnozoites. However, lengthy treatment courses and follow-up periods are not conducive to assessing the effective...
متن کاملPrimaquine for preventing relapses in people with Plasmodium vivax malaria.
BACKGROUND Plasmodium vivax infections contribute to a significant proportion of the malaria infections in many countries. Primaquine is the most widely used drug for treating the dormant liver stage. Different primaquine dosing regimens are in use. OBJECTIVES To compare primaquine regimens for preventing relapses in people with P. vivax malaria. SEARCH STRATEGY In 2006, we searched the Coc...
متن کاملHigh-dose primaquine regimens against relapse of Plasmodium vivax malaria.
Plasmodium vivax causes debilitating but usually non-lethal malaria in most of Asia and South America. Prevention of relapse after otherwise effective therapy for the acute attack requires a standard daily dose of primaquine administered over 14 days. This regimen has < 90% efficacy in Thailand, and is widely regarded as ineffective because of poor compliance over the relatively long duration o...
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ژورنال
عنوان ژورنال: Journal of Travel Medicine
سال: 2006
ISSN: 1195-1982
DOI: 10.2310/7060.2005.12306